Improving clinical paediatric research using lessons learnt from COVID-19

c4c experts have published ‘Improving clinical paediatric research and learning from COVID-19: recommendations by the conect4children expert advice group’ in Pediatric Research.   The COVID-19 pandemic has resulted in some challenges which c4c partners have had to contend with in their clinical trial operations. COVID-19 affected access to patients; laboratories; study materials; and availability of…

Details

European research networks to facilitate drug research in children

‘European research networks to facilitate drug research in children’ has been published in the British Journal of Clinical Pharmacology.   Paediatric drug development faces several barriers. These include fragmentation of stakeholders and inconsistent processes during the conduct of research. This review summarises recent efforts to overcome these barriers in Europe. Two exemplar initiatives are described.…

Details

How c4c is improving European paediatric clinical research through partnerships

“The conect4children (c4c) Consortium: Potential for Improving European Clinical Research into Medicines for Children” has been published in Pharmaceutical Medicine.   Clinical trial scientists and their teams, for several decades, have partially succeeded in improving ways on how paediatric trials are conducted. In 2007, the European Union recognised the need to facilitate development of medicines…

Details

c4c publication on efficient paediatric formulation development

“Path towards efficient paediatric formulation development based on partnering with clinical pharmacologists and clinicians, a c4c expert group White paper” has been published by British Journal of Clinical Pharmacology.   Despite regulatory requirements and incentives, paediatric formulations still lag behind adult formulations for medicines used in both adults and children. This is largely due to…

Details

c4c publication on current knowledge and innovations in developmental pharmacology

“Current knowledge, challenges and innovations in developmental pharmacology: a combined c4c expert group and ESDPPP White paper” has been published by British Journal of Pharmacology   A new paper from c4c experts provides a summary of current evidence and provides scientific insight and suggestions to incorporate the latest knowledge on developmental pharmacology and innovative techniques…

Details