The c4c project aims to develop a Pan European Paediatric Clinical Trial Network. As part of the development of the c4c network we are creating a series of podcasts centred on the work of the network.

Insights from c4c’s expert groups

Franz and Saskia are both involved in the c4c methodology experts’ groups, that bring together experts in different fields intending to advise pharmaceutical companies or academic trials during a paediatric clinical trial.

How was this initiative set up? How do patients participate in these groups as well? What requests have been solved until now?

Listen to this new episode to find out!

What’s the KD-CAAP trial? (for patients)

Kawasaki disease is an acute febrile illness of unknown cause that primarily affects children younger than 5 years of age.

The clinical trial “KD-CAAP” studies the effectiveness of adding a new element to the standard treatment for this disease. What are the hopes for Kawasaki disease treatment and patients?

Listen to our podcast with Prof. Paul Brogan, joint chief investigator of the KD-CAAP trial to find more!

KD-CAAP trial (for professionals)

Kawasaki disease, also known as Kawasaki syndrome, is an acute febrile illness of unknown cause that primarily affects children younger than 5 years of age.

KD-CAAP proof of viability study assesses the effectiveness of adding steroids to standard treatment in children with Kawasaki Disease.

Why is it important to improve paediatric patient’s lives? How is c4c supporting this study?

Listen to our podcast with Prof. Paul Brogan, joint chief investigator of the KD-CAAP trial!

The best kept secret of science communication

Why is Science communication essential nowadays, especially for an European Network as conect4children? How to efficiently communicate science? How to overcome the challenges around fake news?

In our new podcast episode, Claudio Fracasso and Lindsey Hunter, the c4c leads for communication, dissemination, exploitation, impact assessment, talk about the importance of science communication and its central role in c4c.

cASPerCF: Proof of viability studies to test the c4c network

c4c have released two new podcasts about cASPerCF, one of the first non-industry PoV trials to test the c4c network’s infrastructure. The cASPerCF trial aims to find the right dose of posaconazole to treat children and young people with Cystic Fibrosis and Aspergillus infection.

In the first podcast, Prof Adilia Warris provides an overview of the cASPerCF trial and in the second podcast, Jacob Bradbury providing a short overview on what Cystic Fibrosis is and how it affects children.

The how and why of COVID-19 vaccines for children

For our first podcast, we focus on Covid-19 vaccines for children and young people, with Dr Federico Martinòn-Torres. Topics that are discussed include:

  • The reason behind the lack of paediatric clinical trials for COVID-19 vaccine
  • The necessity of having COVID-19 vaccines for children on the herd immunity as well as on the individual side
  • Social inequalities linked to school closures
  • The current challenges in paediatric clinical trials for COVID-19 vaccine